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Dramatically defy the signs of aging with SkinMedica Tri-Retinol Complex ES. This unique serum contains a patented MICROSPONGE® delivery system that gradually releases the active ingredients to reduce irritation. The powerhouse of concentrated vitamin A smoothes fine lines and stubborn wrinkles, evens skin tone and texture, stimulates collagen and encourages the regeneration of skin cells. With the improvement of elasticity and firmness, your complexion is left supple and youthful.