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Building on Sirtuin technology, Clinique science uses youth-extending agents to create a moisturizer that helps intensify the nightly cycle of natural repair. Plumped with natural collagen, lines and wrinkles appear to evaporate. Skin gains that energized '8-hour effect' come morning. 1.7 oz.How to use: To decelerate the progress of lines and wrinkles, apply nightly after 3-Step Skin Care System. By day, use Youth Surge SPF 15 Age Decelerating Moisturizer.